Welcome to Week 3 of Hot Hormone Summer!
In Week 1, we explored andropause which is the gradual decline of testosterone in men. Last week in Week 2, we covered menopause which is the point when women stop producing estrogen almost entirely.
This week, Dr. Ramsey is focusing on the stage before menopause that can be confusing and frustrating for many women: pre‑ and perimenopause.
What Is Premenopause?
Premenopause refers to the years when a woman is still fully fertile. She ovulates every month and has regular menstrual cycles. Hormone levels are generally consistent, and she is not yet experiencing the symptoms of hormonal transition.
What Is Perimenopause?
Perimenopause is the transitional phase leading up to menopause. During this time, ovulation becomes irregular which means that some months a woman may ovulate, other months she may not.
This hormonal unpredictability can cause a wide range of symptoms, such as:
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Mood swings
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Changes in menstrual cycle patterns
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Hot flashes or night sweats
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Unexplained fatigue
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Sleep disturbances
Perimenopause can feel like a rollercoaster because hormone levels spike and dip unpredictably. One month a woman might release an egg, then go months without ovulating, then suddenly ovulate twice in a short period.
The Role of Progesterone
Dr. Ramsey emphasizes that there is one key hormone that can help women feel more balanced during perimenopause: progesterone.
Progesterone therapy can help smooth out the hormonal peaks and valleys, easing symptoms and creating more stability until a woman transitions fully into menopause. Dr. Ramsey calls it one of her favorite hormones for its ability to bring calm and balance to this stage of life.
The Bottom Line
Understanding the difference between pre‑ and perimenopause helps women recognize when changes are starting and take proactive steps to protect their well‑being.
Want to learn more about hormone health and the treatments your doctor might not have discussed?
Sign up for exclusive updates on Dr. Ramsey’s new book, Hormones 101, coming this summer.

